What problems are you having with Rom?
It can be tedious, but you can take out all 3 groups of the spiders so it's just you vs Rom. It can be annoying sometimes trying to get in to hit her if she just loops the same attacks like the AoE blast, but it's just a matter of patience really - get in and out after a few attacks, don't get greedy. The ice meteor attack can be either just outrun (watch for her starting the attack then run in any direction) or roll dodged.
Mostly the camera, because I feel like locking on enemies is counterproductive in this fight, I also have to pace my attacks because, for example it skips phase 2 and go all out with 2 sets of spiders on me, hence the overleveled bit. But holy shit I didnt know spider dont respawn, thats a game changer right there, thanks lol
Edit: aaaaand done, thanks guys!