Only think I'd be concerned about is international appeal. Is he a well known character that will drive Europe and Asia to go?
I don't think that matters much anymore. But Spider-Man is still tough to beat overseas. I think that Homecoming will be ahead worldwide, even if Black Panther gets a Deadpool gross.
Transformers 5 is at $167M after a week in China. It is expected to drop around 75% this weekend, putting it just under $200M total.
I haven't talked about it in awhile, but Dangal is still playing in China, and is now past $190M there.
Wonder Woman finished at around $90M. The Mummy will end a tad above that. Alien: Covenant will finish around $45M.