I am at act 3 now and also did my ascension as well, this time without getting hit (too much lol).
Spammed my totem at the boss, it's my best friend.
I think I have to do something about my dmg output. I fought the act 2 end boss for a minimum 30 minutes, it took so long and barely got him but still first try.
Love this game, and this is just one class so far.
Just find it bs that I have to pay for bigger stash.