I'd recommend Hanabi - simple, novel, brain-bendy card game that is very portable. You play cooperatively with each other, which might be an easier sell for people who don't like conflict in games. I've had a lot of success getting new players interested in this game, even though the game is pretty challenging.
Love Letter is good and portable, too, as others have recommended.
Hanabi is pretty portable. That one has a very small box. I have had it for a while but haven't played it yet. I might try that one out during next Monday night's game night, but I am not sure how well it would go with two people, seems like one that is more fun with a group of four.
I saw on the last page that someone was asking about X-Wing and got some responses. I am looking to get into it, been watching a lot of videos and it looks really fun. What is the best way to start off, buy two starters or buy one starter plus an X and Tie Expansion? At this point I am not thinking that I will go for everything released, but my hoarder-tendencies might kick in after playing it and obtaining a couple minis. If anyone has any recommendations, I am open to hearing them.
A question too about X-Wing. Do the asteroids move after being placed? If they don't, has anyone come up with any variants to the game where the asteroids move? I was explaining some of the basics that I had seen about the game to a coworker who initially seemed like a hard sell on it (he has since warmed up to the concept of the game and said that he will play it if I buy it, but he is of the opinion that half the fun of a miniature game is painting the pieces and the news that these are pre-painted put him off of it a bit in the beginning) and when I was telling him about the asteroids, I started wondering if they moved. If they don't move and remain stationary on the play surface, that would certainly be pretty cool if they did roam around. Something could be implemented similar to the way the dragons move upon waking up in Tsuro of the Seas; each asteroid could have a number designation and rolls of dice could determine which way they drift. So then not only do you need to be mindful of flying into one, but you have to worry about one flying into you or drifting into your firing line.
If there is nothing currently like that in the game, it seems like adding something like that could be a cool new element of gameplay.
EDIT: And Karkador, I see a picture of Skull and Roses in the OP. According to BGG, the Asmodee-published edition came out at the end of 2013. I only see high prices on Amazon, people selling it that are overseas, and OOS pages on most online retailers. Is this something that hasn't really hit the US market yet or did the initial print run(s)? That one looks like a lot of fun, but I can't find it anywhere. I'm not really looking too hard though; Jaipur was one I wanted badly a couple months ago and as soon as CSI restocked it I jumped on a copy (and ran up a $100+ order too, just for that game). Jaipur is now readily available, so if Skull and Roses is just in-demand right now, I can wait for supply to catch up. If a game is super-wanted and everyone is waiting on a reprint though I usually see a thread on BGG about it and I don't see many questioning its current availability...